Siemens Westinghouse continued from page 1 (The nanotubes tend to clump together due to Van der Waals forces.) The team did their research during a three-week said Mason, “Genetics and speciation really interested me, and Dr. Amy Sheck turned me on to hybrid sterility. Yuan Yang, a classmate of mine, noticed that Dr. Willis at Duke [University] studies this very thing. I asked [him] to spon sor my project, and, lucky for me, he agreed!” Mason’s project will soon be entered in the Junior Science and Humanities Symposium, another science competition. Lucie Guo and Xianlin Li’s project was entitled, “CpG island methylation of Regional Finalists on a tour of Georgia Tech GADD45? is marker * , JeffHu r of breast carcinogenesis.” The team investigated a tumor-sup- pressor gene nanied GADD45? and found that its DNA methylation patterns (an epigenetic change in the DNA structure where a methyl group attaches to a cytosine base, forming 5-methylcyto- sine) can be used to distin guish between normal and cancerous cells and serve as a marker of dis ease. Guo began conduct ing research at Duke Comprehensive Center the sum mer before her junior year, where Li joined her shortly after. “What led us to pursue breast cancer research,” the pair stated, “is the magnitude of the problem posed by breast cancer around the globe. ... We were interested in finding alternative methods of distin guishing between cancerous and normal cell lines in order to enhance the efficacy of early detection methods.” Guo and Li worked with Dr. Jeffrey Marks and Dr. Wei Wang from Duke University and Dr Tsahai. Tafari and Ms. Leslie Brinson from NCSSM throughout the research and competition process. Claire Reddy and Yajing Gao’s project, “Optimization of Sample Preparation Conditions for the Dispersion of Single-Walled Carbon Nanotubes for SEM Analysis,” dealt with finding ways to pre pare a sample of carbon nan otubes to view with a scanning electron microscope (SEM) so that they were as spread out and unclumped as possible. period over the summer, work ing under Dr. Stephen Craig of Duke University. Craig is an NCSSM alum and has men tored other NCSSM research students, including a team of three who made Regional Finals last year. Reddy and Gao turned their results over to him and are currently under taking another project for Unless you pmUdiiate bi sone type of resoardi, yon can’t evor be certain that sdrara is tor you ” •Luce Goo uid XtenBi il _l Research m Chemistry here at NCCSM. However, Gao indicated, “There is a NASA opportunity of a rocket launch. We could potentially send carbon nan otubes into space and see what [they] do under high radia tion.” Ying Liu and Jeff Hu looked at the effects of an antioxidant, vitamin C, on E. resistant to UVC. “We basi cally decided to do [this proj ect] because I was interested in antioxidants, and Jeff was interested in resistance,” said Liu, “so we combined the two and found a lab. We were very lucky.” Liu and Hu’s summer research was conducted in the environ mental engi- n e e r i n g department of Duke; they worked with Dr. Karl G. Linden for three weeks. Liu and Hu are presently continuing work on their project and want to send their vitamin C treated E. coli into space on a NASA flight. Lee Ricketson and Nick Cook’s project explored the r-process, the most rapid and complex mechanism by which heavy elements are created and thought to occur in supernovae, by investigat ing the equi- librium achieved [dur ing the r- process], which explains the abundance pat terns of elements. The team devised a method for deter mining this state of equilibri um for each nucleus and used decided to pursue this project because it was the only physics research opportunity around campus at the time,” said Ricketson, “I’ve been into physics since the start of high school, and the opportunity to do research is a big part of the reason I came to [NCSSM].” NCSSM has sent students to regional competition every year since * the start of Siemens- Siemens Westinghouse Competition is a pretty good gauge of your dedication to a science or to research,” added Reddy. “If you can still love research after Siemens, it's probably something you might want to pursue in or after col- leg. It's also an invaluable learning experience.” Guo and Li agree. “Unless you par ticipate in some type of “the opporiuiiity to do research is a big part of the reasoD i came to (NCSSND.” -lee Ricketson Westinghouse. “I like Siemens because it is rigorous, presti gious, and the students can win scholarship money. In addi tion, the format reflects how real scientists do and present their work,” said Dr. Sheck, Mason’s advisor. “I think it is important for Lucy and Xianlin with their prize. Buro, Jing, and Lucy listening to a lecture on Georgia Tech’s robotics program. coli exposed to UVC. The team found that vitamin C caused less E. coli to die and that it also caused generational resistance, meaning that the E. coli became more and more it to identify specific nuclei thought to be responsible for the abundance pattern mystery. They had started learning background material during Miniterm their junior year. “I students to learn to do inde pendent work,” added Dr. Bennett, who advised Ricketson and Cook. “Siemens provides some extra motivation for students to get involved in research and put forth their best efforts.” “I like how it’s been judged, mainly on research,” said Gao, “That’s the main dif ference between Siemens and Intel and other types of proj ects.” “What did I like best? I guess the sense of accomplish ment,” said Ricketson, “Realizing something that no one has ever realized before is one of the best feelings I've ever had. I would absolutely recommend that juniors get involved in research/Siemens. With core classes at this school becoming more like the core classes at ordinary schools every year, research will be one of the only really cool things you can do pretty soon, and Siemens will help you immensely if you're looking at really competitive colleges.” “Doing the research and writing a paper for the research,” they say, “you can't ever be certain that science is for you. Through mundanely collecting data, you find out that science isn't as glamorous as others make it out to be. But its rewards are incredible. Learning in the classroom is nothing like hands-on learning at the lab bench. Also, it's a great way to get to meet pro fessionals. We have kept close ly in touch with our mentors who-still, to this day-are valuable sources of inspira tion.” “ I would highly encourage research participa tion during the summer and during the year, but certainly not for the sole purpose of doing Siemens,” Mookerji stated. “The best research that you can involve yourself with is the research that stands alone from science competi tions like Siemens or the Intel Science Talent Search. In my opinion, finding the opportu nity for steady work in a uni versity laboratory under a pro fessor with vested interest in your work is an absolutely wonderful route towards suc cess in research. Yes, Siemens is very prestigious and the consequences of the competi tion may help your pay for the college of your dreams, but the opportunity of carrying out important, unprecedented, and publishable research is one that leaves you with an advan tage over other students that is far beyond academic. Dr. Halpin

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