jilzh6ini6r S DiSGclS©! This century's medical mystery ffithhope, Dennings find a way to cope June 13, 1985 page B1 In-depth features on people, places and issues. jiareno outward signs that this lovely iflloPark home is any different from its Ills. jiliereare only a few signs on the inside jjtihing is different. But those are i of dead flowers with a bright red bow I,[((line’s heart sits on a table near the It visitors. On the table close to the ,few red leaves hang on the dead stems liisimas poinsettia, and directly in front a fresh bunch of Easter flowers sits jHecovered with a week’s worth of dust, aids of a TV game show can be heard ilack room. liorner, not far from the couch, sits a a with a picture of a lovely young lady, I the smile of a high school graduate. i)'C. Denning doesn’t remember getting life flowers, nor does she remember the It she dusted. When asked about the on the bookcase, Mrs. Denning calls lire of her sister. (iT. Denning reminds his wife, 67, that iipicture of the couple’s only daughter, tell, whatever. I get so confused,” says [tnning, nodding her head as if she to when, in actuality, she doesn’t. Denning has Alzheimer’s disease, tee million other Americans, she has kjenerative brain disorder that first iialoss of memory, progresses with the (speech and the ability to walk and results 1,usually of pneumonia. neurologist, encountered a woman who showed all the signs of severe dementia — memory loss, disorientation and hallucinations - even though she was only 51. After her death, he examined her brain and discovered that part of it contain ed clumps of twisted nerve cell fibers that he called “neurofibrillary tangles.” Alzheimer first thought the disease existed on ly in the young, but in the 60s, research discovered the same disorder in the elderly and it became apparent that the disease was neither presenile nor rare. Alzheimer’s disease usually occurs after age 65, but it can strike in the 40s. Early symptoms include trouble with language or personality changes, apraxix (difficulty in performing rote gestures, such as hair combing) and trouble making judgments, such as dressing for winter in midsummer. Mrs. Denning is still in the early stages of the disease. She can’t remember what she ate for breakfast or dinner or even if she is hungry. She can’t remember members of her family or friends or how to care for herself. But she remembers with ease things that hap pened in her early childhood, says her husband. “Her memory of recent events is completely wiped out,” he says. “All of us suffer some memory loss, but this is different. She’s not try ing to fool you; it’s just completely wiped out of her mind. There is a loss of brain cells. There is no replacing it.” For example, Denning says his wife’s brother often will come to visit her and stay for hours. Shortly after he leaves she will complain that her brother never comes to see her. She also went , .y... "It's the worst thing I have ever come in contact with. You can't explain it to anybody. If I had just one-half hour to discuss anything with her... I never will reach her anymore." liimer’s disease strikes people of every *iisocio-economic group, and the •“teases has expanded rapidly with the the nation’s elderly population. •'feg to an article in Newsweek, ■f’s disease has become “the disease of •®y.” About 7 percent of the people 8 it the United States are severely disabled the lives of more than 120,0(X) ‘*tiyear, including actress Rita *ibnd artist Norman Rockwell. It has Jfc fourth leading cause of death among litter heart disease, cancer and stroke. *••8 says he first discovered that ■8 was wrong with his wife in 1976. tit know at first what it was,” he says. I'ke would write down everything. She ijisive notes and repeated the same ® instance, when she would give me a 1st, she would write eggs, can milk, go ''“Msix items and then repeat the first "'I'l think much of it at the time. **on for six to eight months. Finally, I '"ittoseeher.” test after test, and still nobody iitinine what was wrong with his wife, tiling, through a period, says Denning, when every night she would carry on about wanting to go home in Raleigh. Although she was born and raised in kaleigh, she hasn’t lived there since 1948. In order for Denning to maintain his govern ment job in Greensboro, he has hired a housekeeper to watch Mrs. Denning full time. He did that after he discovered her roaming around the neighborhood. Denning remembers one scare during a trip to a conference in Nevada with Mrs. Denning. That was before Denning felt comfortable enough to tell strangers about his wife’s disease. While attending one of his conference ses sions, Denning left his wife with the wives of some of the other men attending the conference. When she tired of the group, she told them she was leaving and wandered off. When Denning came back for her and found her missing, he was devastated. “It was just a nightmare,” says Denning of the incident. “I got in a patrol car with an of ficer and rode all through the campus (the col lege campus where the conference was held), looking for her. Finally she went to a place and wanted to call me at home. Of course, she wasn’t going to get an answer there. Then she ®''erything out that was known,” , inally, they said it was Alzheimer’s r Mthey couldn’t be sure. The only sure II out is a brain biopsy (an examina- u tissue to determine if the disease is ^ • didn’t see the need of that. It’s fine They don’t know what causes it or ' now a treatment. So there is no l^®lheni through that.” i^entiy^ 5^ys jjjg Newsweek article, * disease was considered an exotic ^ ”7 recently has medical science ^'iitavel the Alzheimer’s riddle, loise Alzheimer, a German called her sister in Washington.” When they found Mrs. Denning hours later, she was in downtown Reno. Denning, a quiet man who seems to use laughter and humor to cope with his pain, realizes that his wife won’t be getting any better. “She is going down, down, down,” says Den ning. “It’s not getting any better. She used to be real stout, now she’s thin. Lots of times she won’t eat. “It’s the worst thing I have ever come in con tact with. You can’t explain it to anybody. “If I had just one-half hour to discuss anything with her .... I never will reach her anymore. You don’t know what it’s like ^^'hen both parties can’t converse. “Sometimes you think, why does it have to be this way? It’s really a terrible experience. But a lot are in worse shape (than Mrs. Denning).” Both Mr. and Mrs. Denning belong to a local Alzheimer’s support group. Those attending the meetings are in various stages of the disease. Not only has Denning learned a lot about thq disease by joining the group, but he also has learned what to expect as his wife’s disease pro gresses. “You try to accept it,” says Denning when asked if he can accept the future. “But it’s hard to do.” Denning says he would advise anybody who has a family member with Alzheimer’s disease to accept it. “Don’t get discouraged because there is no Please see page B14 Story by Robin Adams Photos hy James Parker Above, Mrs. Dennings sits quietly by herself; below, the two pose for a family photograph.

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