16 THE CAROLINA TIMES
SAT., SEPTEMBER 6, 1980
After Five Years Of Research Snail Fever
Cure Ready For Human Tests
After five years of
research funded primarily
by the Agency for Interna
tional Development, a
Johns Hopkins scientist
has developed a drug for
mulation that promises to
cure snail fever, a chronic
.debilitating disese that af
flicts up to 300 million
people in tropical coun
tries, principally those liv
ing in Africa, Asia, the
Near East, Latin America
and the Caribben. It does
not normally occur in the
United States.
The scientist is Dr.
Ernest Bueding, an expert
on parasitic diseases and
NEW SNAIL FEVER
CURE READY FOR
HUMAN TESTS
After five years of
research funded primarily
by the Agency for Interna
tional Development, a
Johns Hopkins scientist
has developed a drug for-;
mutation that promises to
cure snail fever, a chronic
debilitating disese that af
flicts up to 300 million
people in tropical coun
tries, principally those liv
ing in Africa, Asia, the
Near East, Latin America
and the Caribben. It does
not normally occur in the
United States.
The scientist is Dr.
Ernest Bueding, an expert
on parasitic diseases and
pharamacology at the
John Hopkins School of
Hygiene and Public
Health. He developed a
formulation of the drug
amoscanate that cured the
three major forms of
schistosomiasis (snail
fever) in laboratory mice,
hamsters and monkeys.
Amoscanate is manufac
tured by the Ciba-Geigy
drug company of
Switzerland, and was
originally developed as a
treatment for hookworms.
Dr. Bueding's research
was financed primarily
with a $650,000 AID
grant, with supplemental
funding from the National
Institutes of Health. He
noted that the AID grant
expires next month and
said his continued
research and testing would
require additional funds.
"This is the way
American science and a
few American dollars can
change the lives and pro
ductivity of hundreds of
millions of neoDle in
Sears
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developing countries,"
said Douglass J. Bennet
Jr, Administrator.
Dr. Bueding says his
formulation is ready for
clinical tests on humans
and plans to ask the Food
and Drug Administration
for permission to conduct
clinical trials on human
volunteers.
"I am sure that there
will be no problems with
the effectiveness of the
drug on humans," Dr.
Bueding told AID of
ficials, "but we want to be
absolutely sure i is safe.
That is why we will con
duct human tests." AID
would be able to provide
the drug to people in
developing countries once
it is approved by the FDA.
People afflicted with the
disease tire easily and can
not work efficiently or at
all. Snail fever therefore
cripples the local
economy. In some areas,
up to seventy per cent of
the population suffer
from the disease.
According to Dr. Alfred
Buck, tropical disease ad
visor in AID's Office of
Health, "the Chinese
government has already
experimented with the new
formulation on 50,000
people quite successful
ly." He said two to three
million Chinese suffer
from schistosomiasis
Dr. Buck said, "The
drug appears to be effec-
ive against all three major
forms of 'schistosomiasis.
A single oral dose of the
new formulation appears
to be effective against all
three major forms of
schistosomiasis. A single
oral dose of the new for
mulation appears to be ef
fective agaisnt the three.
The new drug seems to
have no bad side effects
and will be cheap to pro
duce. "To effectively control
schistosomiasis," Dr.
Buck explained, "we need
drugs to kill parasites in
man, chemicals to kill
V-l Mi
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Teens On Patrol
At a Rochester playground, Sgt. Thomas Giammarva, left, goes over some points with, from
left, Teens on Patrol members Terrence Clark and Kim Steele, and Community Services of
ficers Thomas Nagel and Kenneth Patterson. The innovative Teens on Patrol program, a ven
ture that unites youths and police in a common cause, is in its 14th year. It is supported by a
grant by Eastman Kodak Company.
NORTH CAROLINA
Widow Gives To NCCU Living Legacy
Mrs. Doris Alexander
of Normal, Illinois, has
made a memorial con
tribution to the "Living
Legacy Fund" of the
North Carolina Central
University Foundation, in
the name of her late hus
band, H.W. Alexander.
The gift was designated
for the use of the NCCU
Academic Skills Center,
according to William P.
Malone, executive director
of the foundation. H.W.
Alexander was the first
director of the Academic
Skills Center, which per
mits NCCU to admit
students with remediable
difficulties in basic
academic skills.
Thomas A. Edison received his last patent when he was 81.
snails in water, and a
public education program
to make people aware of
the danger of infected
water. In addition, we
must provide safe water
supplies and better and
safer latrines."
Man is infected with
schistosomiasis by tiny !
parasitic schistosome
worms. The larvae stage
of the worms leave water
snails and penetrate the
skins of people who wash,
paddle or bathe in water
contaminated with human
feces and urine.
"While amoscanate.
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kills shistosome worms in
people, nothing will keep
people from being re
infected if they continue
to come in contact wth in
fected water," Dr. Buck
added.
The disease infects the
intestines, bladder,
kidneys" and liver, and
creates distended bellies
filled with water. It drains
the body of the energy and
may lead to slow and pain
ful death.
Parasitic and other
tropical diseases "
notably malaria, snail
fever and river blindness
' are major causes of,
death and disability in
developing countries.
AID's primary health
care strategy to improve
the well-being of poor
people in developing cout
nries consists of four key
parts: broad, community
oriented networks to pro
vide low-cost primary
health care services, in
cluding maternal and child
health, nutrition and
family planning; better
water -and sanitation;
selected disease control;
and health planning.
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