SATURDAY, MARCH 1, 2013 - THE CAROLINA TIMES -9
Community Scene
Clubs & Socials
Sisters Network Triangle NC
Sisters Network Triangle NC will host their lOth Annual Surviv
ing & Thriving Symposium on Saturday, March 1. 2014 from 10
am - 2 pm. at the Millennium Hotel 2800 Campus Walk Ave. Dur
ham. NC 27705. 1 he I heme: " A Holistic Approach to Thriving
After Breast Cancer". The guest speakers will be Dr. Kells Marconi
and Dr. Neil Spector. I he cost is $30. and can be purchased from
http:''vvvvvv.sistersneivvorkinc.org . l or more information, contact
Sisters Network Triangle NC email: triaimlenc a sistersnetworkinc.
org. Phone: ( 919)490-1571.
Register to Vote
REV. DR. WILLIAM BARBER
Chapel Hill-Carrboro Area Alumnae Chapter
of Delta Sigma Theta Sorority, Inc.
Celebrates 35 Years
I he Chapel Hill-Carrboro Area Alumnae Chapter of Delta Sigma
I beta Sorority. Inc. w ill celebrate the 35 th Anniversary of its char
tering on Saturday. March 15. from 12 noon to 2 pm at the George
Watts Hill Alumni Center on the campus of the University of North
Carolina at Chapel Hill. Reverend Dr. William Barber II. State Con
ference President. NC NAACP. will deliver the program's theme.
"Standing loday lo Build a Better Tomorrow" which highlights
the sorority 's emphasis on social action and social advocacy. Delta
Sigma I beta Sorority Inc., an international public service organi-
zalion with over 300.()()() college-educated women, was founded on
January 13. 1913 on the campus of Howard University in Washing
ton. D.C. and is the single largest predominately African American
womenaC organization in the country The Chapel Hill-Carrboro
Area Alumnae Chapter, chartered on March 19. 1979. serves Orange
and Chatham counties and continues the legacy of public service
under the sorority aC IM s live point programmatic thrusts: economic
development educational development, international awareness-and
involvement. phy sical and mental health, and political awareness and
involvement. .
Admission lo the luncheon program is $50 and tickets can be ob
tained from co-chairpersons of the event. Dr. Sybil Henderson (919
4l9-l025)or Dr. Maiy Phillips (919-967-4977). The deadline date
lor tickets is I ebruary 15. and proceeds from the luncheon will be
donated lo the NC NAACP.
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Fruit Fly’s Pruning Protein
Could Be Key To Treating
Brain Injury
A protein that controls the metamor
phosis of the common fruit fly could some
day play a role in rexcising brain injuries,
said Duke University researchers.
Ibis protein directs both the early
dexelopmeni and regrow ih of the tiny
branches that relax information from neu
ron to neuron. Known as dendrites. these
thin structures that resemble tree-branches
are responsible for receix ing electrical im
pulses that Hash throughout the body
Incorrect dendrite dexelopmeni or inju
ry has been linked lo neurodevetopmcnlal
or psychiairic diseases in humans, such as
autism, schizophrenia and fragile X syn
drome.
Under normal circumstances, neural
communication is easy much like neigh
bors talking oxer a fence. But if a neuron
is injured or malformed, they frequently
don’t have the proper dendrites needed to
be functional.
"One of the major problems with ilk
nervous system is that it doesn’t regenci
ate very well after injury." said Chay Ku«? .
M.D.. Ph/D.. the George W. Brumley as r
sisianl professor of cell biology, neuro
biology and pediatrics. "Neurons don
multiply, so when they ’re injured, there--
a loss of function. We d like lo know how
to get it back."
While prompting such regrowth in ilk
human brain isn’t currently possible, den
ilrilc regeneration anil arborization — ilk
branching out of dendrites from the body
ol the.neuron — arc a necessary part of II
Iruil Ily Drosophila’s life cycle. In the I;
\al (or worm) state, the Ily’s nerxous sys
tern is attuned to •. h it the smooth-skinned
worm needs: Inkling food, locomotion ;ukL
avoiding allack. As an adult with bri^He?-
coxered skin however, the nervous sy stem
must be w ired for Ily ing. finding mates and
layingeggs.
Until now, researchers haven't under-'
stood how drosophila sensory neurons
arc able lo create two separate dendrite,
branching patterns that successfully ser.VK..
diflcrcni kinds|of sensory environments
said Kuo. who is also a faculty mcmbei
with the Duke Instimic for Brain Science
1DIBS). His team set out lo find the genet
ic mechanism that makes it possible. Hu.;
research, funded by the Alfred P. Sloan
I oundation anil the George AL .lean Brum,
lev. Jr. I ndowmcni. will appear online m
the I cb. 27 issue of Cell Reports.
I he answer lies in the insect's meta
morphosis from larvae lo adult'. During,
this transition. Drosophila lose the neurons,
they won't need for adult life. I he remain-.,
ing sensory neurons sever their dendrites
and grow a completely different set. The
regeneration process, which is controlled
by the hormone ccily sone, is much like
pruning a tree in spring.lo make room for
new growth. Kuo said.
lo find out how the drosophila sensory
neurons accomplish this change. Kuo’s
team lagged abdominal sensory neurewr
with green lluorescenl prolein (GI PCanTI
followed them through niciamorphosts±'_
see if their dendrite branching changed .
I he dendrite design and architecture was
in lack different in the adult stage.
A lest carried out by former graduate
student Gray Lyons revealed Cysteinc pro
teinase-1 (Cpl).is responsible for regular
ing the regeneration of neuron dendrites
and innervating the adult sensory field.
Kuo’s lean! demonstrated that without
Cpl. drosophila sensory dendrites cannot
regenerate after pruning.
I \isting literature also pointed Kuo’s
team lo a parallel between the drosophila
nerv ous sy stem and mammals.
"We investigated whether it was possi
ble that (. pl. during metamorphosis, shut-
lies from the cy toplasm into the nucleus to
cleave a transcription factor required lor*
dendrite development, and makes it a new
transcription lactor lor regeneration." Km
said. And. that turned out to be Irik' " : : - s