VOLUME IV.
NEWBERN, N. C. SATURDAY, SEPTEMBER 22, 1821.
NUMBER 183.
-i
ryTD AND PUBLISHED WEEKLY, BY
PASTEUR $ WATSON,
J 3 per annum half in advance.
FROM THE RICH3IOND ENQUIRER
TYPHUS FEVER.
' 7b M? Efror of the Enquirer. ,
Gentlemen Through the medium
of your paper I will offer some remarks
on the nature and character of a fever
n lt . ol.l.r
fPQtcn is iiu" r . . . i . ,
. - i - rvrpvai iiiv rAciui'-M
r II f in thf?
. Uenbur, Nottaway and Brunswick in
Va and Warren, North-Carolina. This
fever appears to be travelling from west
to east, and some few years .back scour-
counties oi
J .I.r. nortn OTPSl OI IUC rtiniu,V
trJ i i
and
KiJto 1813 it
occasionally
maae us
in tin counties of
Mecklen-
ar and Brunswick, in the form of Ty
prwii Pneumonia.
oor. nrdin 1814. it will be
for
re-
q:uc ,tc- f - n
'JVZra i
- . w .n.A 1
nJre man uu -v -
- .mmffs more than usually cold
a change has perceptibly
taken !
plice in both these respects, our summers
i,,rnmP warmer and our diseases more
violent and more malignant, and yellow
fever Ins shown itself in various parts of
t'ie United States. In the month of Jan
i:irv 1818, a disease made its appearance
ia "the county of uMecklenburg on the
borders of lloanoke in the first instance, &
from thence extended over that countyand
the neighbouring ones. Its attack was
usheredin by a chill, a severe fever en
sued, attendended with a peculiar pun
cent, rather than intense'heat of the skin,
pain of the head and side frequently in
tensely severe, difficulty in Dreaming,
1 .AM.!mrta Vi -rl f r-rn nonf I
full soft and eaiily yielding to pressure:
occasionally a sick stomach, bowels slow, I
urine high colored, most commonly an
expectoration of a bilious blood gela
tinous matter; as the season advanced
snd the weather became warmer, the
pins of the head and side were less fre
quently present, the general symptons of
inflammation were less apparent, the fever
wa less intense, and about midsummer
many attacked complained only of a chill,
slight fever, pains of the head and occa
sionally sick stomach with bilious vomi
tings and diarrhoeas. After a few par
oxysms the fever would entirely subside
a coldness of the hands and feet would
come on with cold clammy sweats, and
the pulse would scarcely be felt; at oth
i times the patient feeling perfectly well
would be suddenly attacked, sometimes
in the field at labour and sometimes in
the house, and fill as if shot, arid lie in a
stupid state with cold feet and hands and
profuse cold sweat and weak thread-like
pulse, but perfectly clear and open in its
beats. At other times again a decree of 1
liquor and lassitude would precede the
attack for a few days, a dull heavy feel
ing of the head would be present, the
blood vessels of the , eyes would appear
red and inflamed and' the eye would be
dull and heavy, frequently watery, and a
general yellow tinge observable about the
fire, neck and whites of the" eyes, with
occasional sense ot fulness of the stom
ach, flatulence, disturbed sleep, slight ten
sion of the pulse, but often full, soft and
yielding the tongue mostly covered with
a thick yellow mucus and fur, urine about
natural in appearance, the trunk of the
bouy warm the extremities cold. These
symptoms after continuing a few davs
uould often in a few hours successively
grow worse, the coldness of the general
surface would rapidly increase with very
profuse cold perspiration, and entire pros
tration of strength and a carelessness as
to events follow; subsultus, stupor and
profound coma would come on and the
tongue would become black, sometimes
rH chopped and dry, and teeth covered
ill dark sordes and the patient lie with
ttery appearance of immediate dissolu
tion being at hand. The pulse, in every
"Stance where to be felt, was clear and
,re in its beats but soft and feeble irreg
and much accelerated. In one case
ct this kind the stupor was periodical, and
absent there was an unusual bril-
-fc-cy of ideas and of the eye, and when
tr?sent, the pupil dilated so as to ob
trjct vision entirely, and occupy the
of the cornea ; in another instance
Wt3-re there was but little fever from the
c3!mncement, a green matter was drawn
,rra the breasts instead of milk by the
e of the glasses, the lady giving suck at
time. There are few diseases on
i!jh the faculty have split more than
!t3 present, strange1 as it may appear.
nartv rrmsidprinir it an inflam.
Gll0ry bilious remittent j the other as
Cumberland moaniainniuacw;v death foiowfed. In another instan
naci ,rrr r ,u,.Mr;erai sympioms oi putresence ca
i i,. vii on r anrjenauuiJ w ,
;32uc -uti - . - . . me I
M KilllAMO r ruin 1I1C 1
a bilioustyphus or typhus leterodes.
i neir practice has been maae-10 corres-
pond with their ideas of the nature of the
disease, and it has been fatal in the sec-
tion of the country where it has prevailed
most beyond example, and particularly in
the county of Lunenburg. 1 hat it owes
its origin to those causes which are pro
ductive of intermittent and remittent fe
vers there can be no doubt: favored in
all probability by some peculiar and in
explicable state of the atmosphere, and '.
think on a careful, diligent and impartial
view of its symptoms and terminations
there can be as litttle of its typhoia and
t r
puma coaracier. in one instance i saw
n : ,l-
a patient in which the disease terminated
m the abscess of the parotid glands, this
was imprudently opened, gangrene ensu
ed, followed by purple spots over the
whole body; the flesh sioughed off the
are and
ce gen-
me on,
nteguments over the os sacrum
j sloughed off leaving the rectum for seve
ral days exposed to view, the ball of the
right eye swelled, projected beyond the
lid, bursted and sunk before death look
r-' U4II1C VII iJ IX lIXI llri ULI3
tu-r was extracted from a lady's breast
smaH m s- . . aDDarent ood
nea'th and yet with the utmost difficulty
gangrene was prevented irom
in another case a young man laboring
under femoral aneurism, in otherwise ap-
paient perfect health, had the aneurismal
sack bursted, the blood was effused be
tween the muscles, intepuments, &c. in
less than 48 hours there were appearan
ces of gangrene, purple sppts were seen
and the leg became black cold and in
sensmie ; in a iew days amputation was
resorted to, when purple spots, vellices,
&c. immediately attacked the other leg,
which continuing spread until half of the
foot sloughed off, when the whole frame
shewed the most convincing: proofs of
general putresency and the stump began
to discharge a bloody saines and death
ensuea. in very many instances ot ca
ses which have terminated fatally, evident
symptoms of mortification have piece
ded, and in a few hours after the death the
face and breast were perfectly black and
large quantities of blood were discharged
from the mouth and nose, and often death
accompanied with a swelling of the corpse
almost to bursting, with a very offensive
smell. That the bilious remittent should
assume this type under an inexplicable
siate oi me atmosphere, is not at all re
markable. It is a fact well known a
.
mongsi an onservant medical men, tnat a
disease rarely makes its appearance a
like at different seasons, or yields exactly
to the same mode of treatment at all
times. It is also a well known fact that
there is generally some one reigning dis
ease to which all others in some degree
assimilate themselves. It is also a well
established fact that during the prevalence
of putrid diseases wounds heal unkindly
and are in an unusual degree fatal, &Jsuch
has on former occasions been the strong
tendency to putrid diseases that bark
and wine have be? ii found essential to
the cure of erysipelas. Even the com
mon pleurisy, perhaps the most genuinely
inflammatory , of all diseases, will neither
require nor safely bear every year the
same free use: of the lancet. With these
facts before me and a close attentive ob
servation of several hundred cases within J
the last three years, I can with unhesita
ting confidence pronounce the fever now
ravaging the counties aforesaid, in 18 out
of every 20 cases, a genuine typhoia re
mittent feverv The inexperienced phy
sician as well as the one who is afraid to
part from his book, and think for him
self, and who labouring under the influ
ence of prejudice and former habits of
practice still persists in the free use of
the lancet, must and will of necessity con
tir.ue to lose- a large proportion of his pa
tients. A few having a hot skin and tol- j
erable strength of pulse bled in a few days
after the attack may survive it; but it is
subjecting them to an unnecessary and
improper hazard of their lives. Those
who are so unfortunate as to have a vein
opened in one of the cold cases, or who
falls suddenly and is bled freely from a
belief that there is depression of the pulse
and congestion of the brain or other im
portant organ, must calculate on deaths
ensuing in 15 out of every 20 cases, and
I believe 19 out of 20 ; for I have never
known but two violent attacks from the
commencement where the lancet was free
ly used but terminated fatally, and those
were preserved by the use of siimulants to
an extent never before used in any coun
try. I have known many instances even
in cases most favorable for the use of the
lancet (judging from the pulse) in which
its use was succeeded by the most alar
ming fainting) and tedious convalescence,
and in two instances where the patient
became senseless and speechless in two
..... " J l T, i r. t
hoars; and died so in less than forty,-
eigni ; ana a mira ia wmcn ne tainted
away for several hours when but a small
quantity of blood was drawn, and died in
three to four days afterwards. I have
seen many, very many of those cases in
j which the inexperienced practitioner
would have incautiously used the lancet,
reduced to such a state of debility by the
operation of a single emetic or catharic
as to require support under it; and wiat
would have been their situation had fie
tawvci. uccu picmiscu ; xci me as aiyiune paiieni. in inese cases Detween the
impartial candid physician to examue
the egesta from the operation of empties
and cathartics,! and say af ter thrs cxami
nation what probability there is of effec
ting good by the use of the lancet J Ev
ery reasonable man must know that the
vital principle cannot be sustained in a
body so completely filled with corrupt
and vitiated bile ; every drop of blood
that is lost renders the system less; able to
bear the operation of emetics or cathar
tics essential for the expulsion of this bile.
That if the secretion of this inordinate
quantity of bile is dependent on inflam
mation: at all of the liver, it is not an in
flammation of the ordinary kind ; else it
would take in every case of hepatitis i
That it is dependent on causes different
from inflamatioh I take for granted be-
cause as far as my observation extends jt
is neither subdued nor lessened by those
means which subdue hepatitis, either in
its acute or chronic stage. Also I am
futher satisfied from the' belief that if the
fever was in such violent inflammation as
to be the cause of such an immense secre -
tion of life, as I have seen discharged by
one patient ounng one niness, inai ei-; unaer n, ano in some iew cases sucnis ine
ther death would speedily take place in j extreme debility and prostration present,
those not profusely bled or the most ob- j that the judicious practitouer will defer
stinate hepatic -obstructions would take altogether the administration of the emetic
place in such a vast majority of cases as I or cathartic for a while, and use freely
to leave no doubt of the character of the j bark and wine toddy with sinapisms, till
disease. I attended a gentleman in this ' watching a favorable opportunity, he will
disease in 1819 who for 8 days in! sue- j procure the discharge of the bile. In
cession took in the forenoon a dose of these extreme cold eases St cannbt be to
tart. ant. and in the. afternoon one of ja- j strongly impressed on the practitioner,
lap and calomel, both of which did their ( that for the salvation of his patient he
duty, and yet in the intervals between j must neither weigh out his bark in drachms
them he would spit out the bile as easily nor measure his spirits, by half pints;
and plentifully as -ambier while chewing if he does, his patient is infallibly lost. -tobacco;
he was supported under their In one of these violent cases, no man
operation with strong mint toddy, and id ; can take enough by the mouth to preserve
the intervals with bark and toddy: he his life : the stomach partaking of the gen
recovered and is now living. I en ti,!iility of the system ejects what is
Again, in inflammatory diseases, 1 be-
lieve theie is not much loss of sensibility
or susceptibility to impressions, and par
ticularly from medicines, and every gen
tleman conversant with the prevailing fe
ver, will admit that if frequently requires
8 and 10 times the usual quantities of med
icines, to produce their ordinary effects,
I have myself given as high as seventy
five grains tart. lant. before it would puke,
and in the summer 1819, 30and 40raias
was quite a common dose, and cathartics
in similar proportions : in one case, I
gave 9 drachms- of calomel in eight days
with a proportionable quantity of ialap.
oil and salts, and it never produced any
sensioie euect eitner emetic cathartic or
sialagogue, and the patient recovered by
the plentiful use of bark, toddy and cam
phor. The cases that occured of pleuri
tic character in January 18,18, were the
first 16 treated in the usual way for pleu
risies, the nrst o or terminated fataily.
As the pain was very severe, and the skin
hot, it was conjectured, blood was too
Paingly taken in the commencement
and accordingly, tne alter ases were
blooded more freely ; they also termi-
nated fatally. This did not occur in ray
own practice, but within the sphere of
rry observation ; but I too bled some
with a little want of success. Finding
that success did not attend the coursepur
sued, and that as the disease progressed,
subsultus and occasionally bilious stools
took place, I altered the practice, and
when I found a patient with a hard strong
nulse I took awav a little blood, then
blistered the pain and gave an
emetic
followed by a dose of jalap and calomel.
whichproduced large discharges of yel
low, green and dark bile; the cathartic
was repeated according to indication, and
wine-whey and camphor julep completed
the cure ; the same treatment with eraet
ics and cathartics, &c. was followed wken
bleeding was not premised, all pain of
the chest being previously removed iby,
blistering ; as an expectorant Barton's
brown mixture, leaving out the opiite,
,was used ; the recoveries were almost
universal and rapid. When I was called
in to the fever about mid-summer, and
found the smallest tension in the pulse, I
gave to a male adult 10 grains calomel,
30 of jallap and i2 tart. ant. . This gener
ally brought on a severe discharge both
upward and downward of yellow, green,,
and dark bile, sometimes looking like tarjj
sometimes indigo mud, sometimes chop
ped ispinage, and sometimes spring moss
in immense quantities ; that from the stoj
mach frequently looking like blueing an
indigo water, but mostly yellow and fre-
quently green. If the strength was suf
ficient, 1 repeated the calomel! with oil.
; or salts, sometimes I preferred1 repeating
me emeuc, u tne aiscnarge from the sto
mach was large and very vitiated, aiid in
this way I continued the emetics ana ca
thartics as long as the pulse and strength
would justify, and it is inconceivable
what quantities of bile a single patient
! would discharge. I verily believe I have
j seen from 10 to 12 gallons discharged ; by
emetics and cathartics if there is a fever,
1 prescribe wine whey every 20 minutes,
with five grains camphor, repeated every
hour till perspiration "co ines on, and the
fever sabsides, when the cure is comple
ted by the aid of bark, Colombo and wine
or toddy and ' camphor. In those cases
where there is a coldness of the exterrr.i
ties from the commencement! or where
tie patient falls suddenly from I being ! in
apparent health, great care and caution
are requisite in the administration of ei
ther emetics or cathartics; for by the se
vere operation of either, be vital stream
is like the water of a mill pond with the
flood gates open, it is ready to rush out
of the body, and nothing but the most
prompt, vigorous and decided measures
can arrest it. Here is a field for the ex
ercise of skill , and sound discretion.
The physician is aware of the quantity
of bile pent up in the stomach and bowels
of his patient, he knows it should be dis
charged, and , to effect it safely fhe must
1 either work off the emetic or cathartic by
1 large drafts of strong toddy after each
evacuation or his patient irrevocably sinks J
taken, a profound stupor ensues, univer
sal coldness and sweat come "on with sub
sultus, and life is held only by the tenure
of skill in the physician. Strong mint
toddy with bark and camphor must now
be taken every half hour, the head is to
be covered with a blister, and sinapisms
applied to the
extremities and breast and
-changed every hour;, one! to two ounces
bark, tvhh one to two gills of good rum
or French brandy, and 60 to 80 drops
laudanum thrown up by way of injection
every 2, 3 or 4 hours, as the urgency 'of
the symptoms of coldness and sweat may
indicate, and continued till there is sore
ness and fullness complained of iii the ab
domen, after which the extremities begin
to grow warm and the coma to cease.
Injections are now to be administered to
procure 2 or 3 stGols, when bark injec
tions are again to be used at such inter
vals as may be necessary to keep ofjj the
cold sweat. In this way ! have frequent
ly used from 10 to 12 ounces bark in 24
hours with the happiest efiectjj in the
desperate cases 30 grams camphor and
20 grains vol. alkali were thrown iup with
each injection. In another 2 table spoon
fulls of bark, two of rum and two of a
mixture of equal parts spts. harts, sulph.
eth. and tinct. camphor were thrown up
every hour for 30 hours, with the very
best effects. Thus patient was attacked
suddehlyj and when 'I first saw him was
to all appearance expiring. An icy cold
ness with profuse sweat was on him, his
pulse imperceptible, his eyes sunk and
his countenance haggard. in the extreme,
with cramp of the arms and legs. In
one hour he took 6 drachms paregoric, 80
drops laudanum, 150 dropsspiiits harts,
1 ounce sulph. eth. 90 grains camphor
and a pint of rum. His extremities were
covered with sinapisms, also the trunk of
the body, and the mustard not drawing
readily, cloths rung out of boiling water
were applied to him, and the mustard af
ter them, and by the use of barU injec
tions as above, in four days he was out of
danger.. It will appear incredible to any
nerson who has never been mucn con
versant with the formidable disease, how
much bark and spirit are absolutely ne
cessary to preserve life in many j instan
ces. With many it is in disrepute, first,
because the quantity is unusual ; 2d, be
cause the practice is unusual ; 3d, because
all do not recover under H ; 4th, because
the proper remedies frequently fall from
novJDeing given m auuivtuu iuauiitics ,
thbecanse they are lrequei)Uy given before
sufficient evacuation, are - premised, and
Oth, because their indhcr&iinauj use is
not suited to every case of the fever, f
know one gentleman now living, who
for 2 or 3 weeks drank two bottles port
.wine and a quart of rum' every 24
hours, and took from 6 to 8 ounces of bark
per 24 hours during the time ; and it is
not unusual for a man to require from 1
to 2 quarts rum per day in addition to the
bark injection, to keep up the pulse, and
indeed this must be done without re
gard to quantity intoxication is almost'
impossible. An extensive practice In the
fever. for the last three' years, in which
time I have witnessed the result of seve
ral hundred cases, induces uie to speak
with confidence of a line of practice unu
sual, except with a few, but daily, becom
ing more general from the success atten
ding it. Should its publicity be the means
(and I know it will if followed) of pre
serving the lives of my fellow-citizens, I
shall be gratified and content.
t One patient drank 7 gallons spiritp
in 8 days was fairly convalescent on it,
but being reduced by a purge and put to a -quart
in the absence of this physician, he
died from its insufficiency to support him.
! - MEDICUS.
August 27, 1821.
; FOREIGN.
OS& DAY LATER FROM LONDON. ,
; Boston, Sept. 8.
By the General Green, Halifax pa
pers to 29th tilt, have been received from
our- correspondent. They mention the
arrival at Halifax of the Sandwich pack
et from Falmouth, with London dates to
the 17th July, being one day later than
was received by the Tuscarora at Phila
delphia. The final preparations for the
Coronation were; making,' which was to
.take place on Thursday, J9th July.
LONDON, JULY 17.
THE QUEEN.
Tiae report that the Queen has taken a
house in Great George-street seems not
to be true. -We were willing fo credit it,
because, that street being within all the
barriers, sht might proceed from it, on
the morning of the Coronation, to make
whatsoever claim of t admission she plea
?es, without I hazzarding the public tran
quility. All that is alleged to be requir
ed of her feelings all tjhat might be held
too humble in a voluntary absence from
a ceremony, of which the Privy Council
has declared that she had no right to
form a part whatsoever might be rep
resented as disadvantageous in so deco
rous a submission. All this might be
prevented;, all her claims might be fully
made and formally recorded, with ease to
herself and others. k
No alteration of the Queen's intention
has yet been announced. A former col
umn contains some statements upon this
subject. Yesterday, as if the ample Re
ports, iven by the newspapers of Mr.
Brougham's argument on her claim to be
crowned were not sufficient, what is cal
led " an official publication", of it was
made, to. which the following precise 'no-
lice was affixed. . ,
" Her Majesty has been pleased to
command that the grounds of her clafms
to be crowned, as stated by Her Majes
ty's Attorney-General before the Lords
of the Privy Council, should be made
public. ' !
(Signed) "HOOD.",
" Queen's-house, July 10, 1821."
Paris papers of the 13th contain but
little intelligence of any interest. The
journals of opposite politics have, skir
mished a little upon the character and
fame of Bonaparte. But we find nothing
worty extracting. The cancer contro
versy is also I noticed, and the following
medical opinion given upon its charac
ter, from the' Dictionary of Medical Sci
ences " Climate has no influence on can-
cer its two usual causes are, deep and .
protracted sorrow and excess of drinking "
spirituous liquors."
A mail ha arrived from Hamburg with
papers to the 6th inst. A t eport is said
to haveprevailed at Vienna, that Rus
sian troops had entered Moldavia upon
the ground of the Tuiks having violated
the existing treaties, by occupying Wali-
chia without the consent of the Russian
government.
Pajs papers of' the 14th inst. reached
us this day. The King continues to take
nis airings near ji- x
and Toulon great activity is stated to.
prevail. Scarcely do any vessels of the
royal navy arrive, without being speedily
equipped for new expeditions. The
Cleopatra frigate has sailed for India and
China ; the uaccnanie gainot is to join .
' the Normande, which is on her voyage
for Madagascar, Vice Admiral Halgin
: has been appointed to the command of
the squadron in the Levant.
-
'I