■gWf IS ft 3-8 SANFORD, NORTH CAROLINA, WEDNESDAY. JANUARY 21. ISfll ~ 1 kora s SECRET; - , We Describes the Curative Lymjjtvantf ' How He Discovered' It. T\ JSwtln .Vpi cint-to fhr Neve Xarii £ *»■ , : Professor Koch, in liis coromuni ■•ycntioh to a medical journal making, known the'composition of the fa mous corativo lymph, says: “So , fa? ns-;] have been able to review the many statements published and oothBYiMucstions received*-my indi cations liaVe I teen fully and com* ' ^netely confirmed. The general - consensus of the opinions thus ' ex pressed is that the remedy has a dspegijfc effect upon the tubferculai •itiifisaiS;and is, therefore, aupfieoEle is a vory delicate,and sure reagent for the discovery of latent, and the diagnosis of doubtful tubercular processes, . Most of the reports re ceived agree that mauy of the [na tion ts have shown more or less , pronounced improvement. Iii not a fevv'casivs ateure has beenoffeeted.” Continuing, the Professor says that the allegation is made that the . lymph actually promotes the tuber • culous process. During the past six vqeks'of his experience, both as to its curative effects and its efficacy, as a diagnostic?, he has- applied it to about one hundred and fifty persons »• suffering from tuberculosis of varied ...types,. Everything developed in . that, experience, the "Professor says, 'mvnk-d with his', previous obser vations, and nothing happened to, moke necessary a modification of w,ii.'4 lie has heretofore reported. -The • possible -application of the principle underlying the discovery .. to the treatment of oilier diseases ‘•lbair those of a tnbereulous nature drio.aods^ou the. part of the, oper ator, a full knowledge of the char-, peter or the remedv. '; ■« KOW THE OIBCOVESY-VaB MADlE. ' “Before going into the remedy itself,” says Professor Koch, “I deem it necessary to state tha-way I ar rayed at the discovery. If a healthy guinea pig be inoculated with the . pure German kuUur ipf, tubercle bacilli, the, wound caused by thein „^cii]i[tioa mostly closes over with a sticky matter and,,appears, iij its; .e.rny di»yfs,“tStt»«il.'?? After tefi -to ■ Tcntrretu a ay a a nara noauie pure ara Sir itself, which/V'cm breaking;, fourns an. ulcerating sore, which ■ continues until the animal dies. . . -'•Quite a different; condition of • tilings occurs vyhen a guinea pigv«l veudv Htiiferiog from tuberculosis is inoculated. An animal successful , !y inoculated from four to six weeks before is best adapted for this purpose. In such,; an animal- Urn small indentation assumes the same et.tnky covering at the begiuning, but no nodule forms. Qn--the coir* trary, on tue day roUowmg or' the ■ wool)(I day after thtP'iiwculatiQrv the phree where the ly7upli%mject ed shows a stange change.' It be^ . comes hard and assumes a darker coloring, which is not eonfied. to tJjo_ • inoculation spot; but spreads to the neighboring parts until itat,tMns,a diameter of 05. to1 centimeter.’ lii a few* killed by a somewhat prolonged apjVlhaition of a low temperature of j /boiliiig host, or by means of certain chemicals.* 'This peculiar fact I ’ followed up in all directions, and ■■thisfurther- result- was obtained; that killed pure cultivations of tuber* ctilar bacilli, after rinsing in .water. • m.jgh V1 injected in great quantities uudu- heflithj. guinea pigs’, skin, vitbortrajiy."effect occurring beyond ifoflii npurat ionr l JE.&. , ■* , ' "f *>•««' f unions guinea pigs, on th< ~ other liuud, are killed by thd injec :£ r tions of very small •' quantities of. 'such diluted cultivations. In fact, within six or forty-eighthours, ac cording to .the strength of the dose, an injection which is not sufficient to produce ' the death of the ahimal may cause extended necrosis to the skin in the vicinity of the. place of injection.-" If the dilution is still further, diluted until it is scarcely visibly clouded, the animals inocu lated remaiji alive^ and a noticeable improvement in their condition soon supervenes; If the injection's are, continued at intervals of from one to two days, the ulcerating inocula tion will become smaller, and finally scar over, whieli otherwise it never does; the size of the' swollen lym phatic gland is reduced, the body becomes better nourished and . the morbid process cease, unless it has gone too far, in which case tlie an imal perishes from exhauston.’’ THE OUBATIVE SUBSTANCE. After giving further details of his experiments, Professor Koch says that anything jvhich is intended to have a healing effect in tuberculosis must be in its nature a soluble substance, which would be lixivated to a certain extent by the fluids of the |bdy*Joatiri&;i around the tuber cle, bacilli, and be transferred fairly and rapidly into the body. Mean while, tlie substance producing sup puration apparently remains behind in the form of tubercular bacilli, or dissolves very slowly. • ! The only important point, there fore, was to induce the evidence on the outside of the body of the pro cess going on within, and to extract from the tubercular bacilli alone the curative substance. This, says t}» professor, was a task which de manded much time and toil before, with'the aid of a forty to fifty per cent, solution of glycesdue, he suc ceeded ; in” obtaining an effeetive substance from, the tubercular bacilli.' With the fluid so obtained Professor Kochf made further expe riments with animals, and 'finally with human beings. These fluids were then given to other physicians to enable them to repeat- experi mepfir, «■: ‘ ' OOMPOSITIONOF THELYMPH. Into the simple extract there naturally passes from th&tubercular bacilli, besides the effective Sub stance, all other matter soluble in 60 per centum of glycerine. Con sequently, it contains a certain quantity of mineral salts, coloring substances, and other untinowu ex tractive matter. Sprue of these sub stances can be removed from it with tolerable ease. _ The 4 effective substance itself is insoluble in ab-^ solute alcohol. It can be precipitat ed by jt-^iot-i indeed, ih a condition or pertecc purity, but when suit combined witli other -.extractive 'matter. The coloring matter may also be removed, so as to render it possible to obtain from tha. extract a colorless, dry substance, contain ing*1 the effei tive principle in a ranch more concentrated form than original glycerine solutions. For appplication in practice this purified extract offers no advantage. | The pnrfication process would al so make the cost of the remedy unnecessarily high. Regarding the conSlituUim of more effective .sub stances, Professor Rocb says that surmises otriy-can.be for the pres ent expressed. These subglauces appear to him to bo derivative from albuminous bodies having a close affinity to them.. extract does not belong to the so-called group.of tox-albumeus, because it l>ear# a higher temperature, and in dialysis, goes easily and ■ quitjkjy through the membrance. The pro portion of the effective substance it the extract is, to all appearance Very small aud is estimated at frac tions of 1 per centum, which, ii Correot, shows that we should huvi to do with matter the effect oi which, upon organisms attacked with tuberculosis, goes far beyom whafc:-b known of ‘the strongs ' arariotr of th« kkmkuy. Regarding the manner in whlcl the specific action of the remedy on tn berculosis tissues is to he repre ss ted, Professor Koch says': J,Va rious hypotheeis may naturally be ! put forward. Without wishing to affirm that my view affords the best explanation, I represent the process myself in the following manner: The tubercle bacilli produced, when growing in living tissues, the same as in artificial cultivations, contain' Certain substances which, variously and notably, unfavorably 'influence living elements in their vicinity. Among these is a substance which, in a certain degree of concentration, kills, or so orders liying protoplasm that it passes into a condition * that Weigert describes ns coagulation nacrosis.v ■ ; —“In tissue thus become necrotic, the bacillus finds such unfavorable conditions of nourishment that it can-grow no more, and sometimes dies. This explains the remarkable phenomenon that in organs newly attacked with tuberculosis, for iu-‘ stances, iu guinea pigs’ spleen and liver, w,hjch than are covered with gray nodules, numbers of bacilli are found, whereas they are rare or wholly absent when the enormous ly enlarged spleeeti consists almost entirely of whittish substance in a condition of coagulation necrosis, such as is often found in cuses of natural death in tuberculous guin ea pigs.' -< “The single bacillus cannot, therefore, induce necrosis at a great distance, for as soon ‘as negrosis at tain a certain extension the growth of the bacillus subsides, and there with the production of the necroti zing substance. A kind of recipro cal compensation thus occurs, caus ing the vegetation of isolated bacilli to remain so extraordinarily re stricted, as, for instance, in lupdf and scrofulous glanus, PEOBLEMS TO BE SOLVED. Continuing his explanation, Prof Koch says that the remedy contains a certain quan tity of recrotizing substance, a large dose of which injures some of the tissueelementseven in .a healthy person, ana, pernaps, tin* wnite blood corpuscles or adjacent cells, thereby producing fever and a com plication of symptoms. In the case of tuberculous T patients a much smaller quantity suffices to induce at certain places—namely, where tubercle bacilli are vegetating, and have already impregnated the ad jacent region with the same necro tizing matter—necrosis of the cells, with the presentation of phenomena in the whole system. Thus, for the present at least, it is impossible eith er to explain specifically the influ ence .which the remedy will, in ac curately defined doses, exercise np pn tubercular tissue, the possibility Of increasing the do«es with such remarkable rapidity as has been sug gested, or the remedial effects which have been unquestionably produced under not too favorable circumstan ces. QUAY’S FORCE BILL. Washington, Jan. 12.—Pennsyl vania’s Senators are not losing op portunity after the nomination of Cameron, in spite of the opposition of the administration, to indicate to the President how. little the Sena tors care whether the . President is pleased with the course which they think they ought to pursue. - Last supmer, when the Force bill was being considered in the House, and after it had gone to the Semite, there was some talk about the inten tion of Quay to introduce a bill that would be at once a more candid as \ well as a more offensive proposition ! thuu that one which Mr, Lodg' had allowed Mr. Rowell to report, but which has been known as the Lodge r bilk The Quay bill did not appear, and it was assemed that the report , that he had a bill like, that described was incorrect,. Senator Q uny main j taiped his usual recticicence when . he was approached for information, but he had his bill all the time, and he hung on to ithintil to-day, when i he introduced it in the Senate. • For the most part, it ip, in its provisions h good deal like the Hoar bilk. A few sections at the begin ning, in fegard to registration, dif fer from the Horr bill, but there are man/ sections cut out of tlm Hoar bill as reported in the Senate These are amended in places in h way to indicate that' Mr, John / l. Davenport was not consulted 'by Mr. Quay in fiixing the compensa tion that the supervisors are' to5 ;rc eeive, for they are put down at not exceeding 12,500 a year, and- then only in large cities. The real interest in the Quay bill is the last section, which provides Cor the suspension by the President, of the writ of habeas corpus in pla :es where it is found impossible to secure peaceable *>nforcement of the law, and the permission, to put a bullet behind every ballot, and ih :he motive of Mr. Quay for intro, lucing a bill which, at first sight, seems calculated to intensify the opposition that has been expressed by conservative and peaceable per sons for the Force hill ever since it oegun to understood as as a meas ure to constraiu the black vote of 'he South for the benefit of the Re publican party. ; As nO one could be assuturned to inow better than Mr.-Quay what is ntended by his bill, .a correspon )f the Times asked him this after loon to tell the paper something ‘bout it. The “silent man” did not lutter away into the Senate Cham ier or ask to be excused. “It seems to me,” he suggested, that the bill pretty well explains tself. Where it differs in its pro visions from the hill reported to the Senate, I think is stronger, but the ■eally important part of the bill,. I ibould say, is the last section." “But that brings in the military,” vas suggested. — • ' “Yes”’ answered the Senator; ‘but is we must really have a Force bill, why should we not make provisi on in a way that cannot be misuu lerstood, for carrying it into effect ? L.have no doubt that it provoke dis cussion if an attempt should be made to get the Force bill up again. Having no other means than those that you or any other newspaper reader has of ascertaining public opinion on the subject, I should say that there was not much expecta tion that the measure.-should,• be again discussed at this session; but if it must be considered, I think the Senate ought to have a text from which some plain and outspo ken talk can be heard.” The Senator walked away with a complacent smile lingering above Ids bright rod necktie. He had spo ken plainly enough, but his smile “spoke volumes.” >v Philadelphia Times. Senator yuay s new andimproved Federal election bill is' apparently lesigned to make auy sort of Force legislation impossible by making its true character plain to everyone. Quay’s bill does not differ essen tially from the Hoar bill', except that it goes straight to the mark, and instead of .disguising the bay onets it presents them boldly. When it is necessary to overthrow the law and count in a Congress, Senator Quay proposes that the President shall taka the full responsibility and do it in the regulation' way. He is to suspend the habeas corpus and call out the army. '> There can be no question, that Q»ay’»,bill is an improvement upon Hoar’s, in so far its it expresses; its purpose more honestly and in a way that the country cannot misunder stand. It needs not be supposed .that Quay expects this bill or any like it to pass. He -simply wants his party to know*, what a Force policy really means. Bucklen’s Arnica Salve. Tije Best Salve in the world foi Cuts, Bruises, Sores, Ulcers, Salt ltheum. Fever Sores, Tetter, Chapped Hands, Chilblains, Corns, and all Skin Eruptions, add positively cures Biles, or no pay required. It 'is guaranteed to give perfect Satisfaction or money refunded/ For sate by Mcl vers. ~ HOW NEW YORKERS LIVE. The City Hedged by Rivers—Passen* tiers and iay Gould’s L Roads— Brooklyn Mattel s. y-X. Correspondence SlatcsrUle Larul Strangerc frequently remark on on the great number of restaurants in New York. It is because New York is not a city of homes. Near ly all the people here who don’t bear’d, live in flats or apartments. There are few homes in the South ern sense of the word “home.” Peo ple of moderate meens who want homes live in Brooklin or some su burban village ten or thirteen miles away. The absence of homes is the chief reasons for so many restaur ants. It is also the chief reason why there are so many theatres in in the eity. The average young man has but two ways in winter time of seeing.his girl alone. One is to take her to dine or sup at a restaurant, and the other is to take her to a theatre. The former is the most popular. From Delmonico’s down, all the restaurants in town are fairly well filled for two or three hours every night in the week ex cept during hot weather. Some times a couple will set at a table a whole evening making love over a dish of oysters. The prices at most of the restaurants are quite reason able. You can get a good dinner of five courses with a bottle of clar et wine* for fifty cents, and an ex cellent one, with wine, for a dollar. At one of the largest cheap restaur ants—where, it is said five thousand people sit down to table daily—the guests are regaled with music in stead of wine, a string band being placed in a balcony at one end of the room. ' Many the larger flat houses have restaurnts connected with them at which • the occupants of the several floors take their meals. Of course all this is deplorable. New York would be a much health ier place moially if every family could liave~a house to itself. The devil loves a crowd. It seems to be characteristic of the human race that moral elevation follows segre gation and moral turpitude compan ionship. We all know that coun try people are the most religious of any. What quiet, sober-sided, well ordered towns Brooklyon and Phil adelphia are as compared with New York! Both of them are home towns. New York is simply a great big hotel full of boarders all bent on “having a good time.” THE CITY HEDGED ABOUT. No doubt there would not be so much crowding if landowners would not hold building sites YtT such outrageously high figures: There is land enough on Manhattan island to supply the population com fortably if the population'* were' al lowed to use it. But it is fenced off and held for speculation, the growth of the city being consequently hin dered to a very great degree. The main strength of the lund-gluttous lies in the fact that New York is on a small island and that communica tion with the main land is inade quate to the needs of the main pop ulation. If there were half a dozen bridges across the East river, and no river where the Harlem now is, rents in Gotham and the prices for vacant lots would be reasonably low. It is unfortunate that the government is now at great expense m deepening the channel of the Harlem river, instead of filling that useless stream up. Some misguided New Yorkers, with a misguidud newspaper or two, have urged the construction of this Harlem “ship canal,” as they call it, when in real ity the Harlem is already a barrier to the growth in the city in the on ly way in which it can grow at all _ TRANSIENT FACILITIES. It is to be hoped that the ques tion of repid transit facilities for tli city will bo settled by the Legisla ture this winter. Six hundre thousand passengers are carried ii thd L trains every day. So sayi -.(i wide smili "■ v .... as he pats his pocket'book. “Let’s have some more L roads,” cays Mr. Goujd. Whereupon the New York Sun advocates editorially building at least one more immediately. But happily Mr. Jay Gould and the edi tor of the Sun are not liked in this town and are not heeded when they advise. There will be no more L roads here. Six hundred thousand passengers a day are six times too many . for comfort as the suffer ing six hundred thousand who trav el on the L roads will tell you. And that fact has made roads as unpop ular as Jay Gouid himself, which is very unpopular indeed. HAJOB CHAPIN' BECOMES UNPOPULAR. It was not long ago that people said of Alfred Chapin, the wealthy mayor of Brooklyn, that he might one day be Senator and one ,day be Governor and one day be President of the United States. But they say now that it is improbable that, after his present term expires, he will ev er be even so much as mayor again. Public distrust throws a shadow to day on the man who a month ago stood in the sunshine of public ap probation. The Water supply Company of the city of Brooklyn is a company which but a few months ago was in a moribound condition. Its presi dent declared on oath that its stock was worth only $50 a share. That no business man of wisdom wished to own any considerable number of its shares was a matter of common knowledge; that it would soon be a defunct corporation was a matter of common expectation. Suddenly the city of churches is startled with the announcement that through the instrumentality of Mr. Alfred Chapin, he has become sole’ owner and proprietor of said Water Supply Company by paying for each and every one of its shares, the astonishing price of three hun dred dollars, besides assuming two mortgages amounting to $500,000. And so now Mayor Chapin is de manded to come in to court and de fend himself against a charge of maladministration of office. D. T. D. MODERN DEGENERACY. ^ rank Leslie's Illustrated Netcspaper. What occult forces are at work to wreck the finest sensibili ties of men and women? At no time within the century has there been in the literary iinarket such a deluge of vicious, trashy, immoral literature. The worst productions of the realistic school are greedily reproduced and as greedily read. The nastier the novel the greater its popularity, the larger its sales. On the stage there is likewise a notable slackening of moral tenden cies, a devotion to the suggestively impure and the wretchedly wicked Perphas thisis an outcome of the dangerous literature that floods the book-stalls and news-stands. The mind satisfied with Zolo finds noth ing to shrink from in the presence of a naked woman on the stage. There can be but one outcome to this indirect contact with immor ality. In the end. it means direct association with impurity. When the newspapers are crammed with reports of elopements, soeiul indis cretions, and offenses against moral ity more or less hideous, it is be cause their readers enjoy the privi lege of paying for such things. Morbid fanoies seize the victims of modern criticism, and they seek safety from themselves in death. There is a prevalent deformity in the human mind, a ghastly fondness for the vile, if not the villainous. We have a new-fangled idiotic “passion in peotry” as well as in art and novel, writing. Women, defi antly put their names-to verse3 that bring blushes to the cheeks of mod est men and the crimson of shame to modest women. In a .Viena court recently a poetess of no mean standing had to defend hersell against the direct and open charge of licentious writing. She went in , to court and boldly declared her de votion to the school of -realism ir • ^ .s-vr- 7 life, und the naked t rutty in poetry. This “school of passion," which ek-'S' isls in Germany and Austria as it has long existed in France, is begin ning to find a foothold in America, ‘ The Aurtrain poetess insisted that she had a right to depict the swell ing of unchained passion to the point of action in order to reveal the misery that may overtake the 1 person causing the downfall of an other, The court, without a mo-' ment’s Hesitation, ordered the con fiscation of her poem. ... Her plea ? was like that of the erratic and fab*. atic Tolstoi in behalf of his “Kreut zer Sonata." It is the plea of a', mobid mind, whose morbidity ap proaches disease, but it is more dan gerous to others than the possessor. It has been said that the church-' es are at fault. That they need, aa*’’ ~ awakening. Perhaps so; but it ». the history of nations that wealth leads to luxury, luxury to vice, and , vice to oblivion. The lust for wealth is the curse of American people. The old New England mother-who toiled at the spinning wheel, and taught at the fireside, whose highest ambition for herself was a sacrificed life, and for her children a life of * spotless purity, seems to to have passed away and been forgotton. , Modern society is getting to be a modern sham. Tfie preachers are. silent because modern society is not too tolerant with them. In former days they dominated the social fa bric. Now they swim with the fast running tide. .Religious fervor, however comes in waves. It is felt with peculiar force at times. Perhaps we are too prosperous. Perhaps because q£. our prosperity there is a natural drifting away from the safest an chorage; but the nation cannot af ford to drift too for. It is time to stir the public mind, to check - the tendency to revolt against restraint, to cheek the impression that liberty is license, and passion, sentiment. . No time should be lost by the press and the pulpit in entering" a protest against poets of passion and novelists of the so-called “real istic school.” These are scattering the seeds of vice far and wide. They are building up in young, alert, and impressionable hearts impregnable fortresses against the assaults of conscience. They are undoing in a day what the church has built up in - years, and assuming a fearful res ponsibility. The warning voice of the poet long since has sung: “Alas! for him whose harp outrun? Thelirst low minor-chord of doubt, And gave that bitter keynote out Whereunto unaccounted souls- --have sung." A Safe Investment. It is one which is guranteod to bring ' you satisfactory results, or return of purchase price. On this safe plan yon can buy from our advertised druggist a bottle of Or. King’s New Oiscovery for consumption. 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